The electronic, ‘paperless’ medical office; has it arrived?

Immunotherapy for Lung Cancer: Has it Finally Arrived?

The possible link between infection/inflammation/immune activation and a cancer patient's outcome from both a causative and outcome point of view has long been postulated. Substantial progress in the understanding of tumor-associated antigens/epitopes, immune cellular subpopulations, cytokine pathways/expression, the tumor microenvironment, and the balance between tumor-immune suppression and s...

The Myth of the Paperless Office

Ch. 1 – Introduction Discusses the origins of the myth. The phrase ‘paperless office’ is traced to Xerox PARC, although they trace the idea of replacing paper-based methods of working all the way back to the 1800s with Samual Morse’s idea of electronic mail. They mention other precendents for trying to do away with paper, moving forward in time from that early date, including digital libraries ...

The Myth of the Paperless Office

Therapeutic arteriogenesis has arrived.

The report by Seiler et al 1 on a clinical trial using granulocyte-macrophage colony-stimulating factor (GM-CSF) to stimulate the growth of coronary collateral vessels is the temporary culminating point of a long history of research that started in the early 1940s with the observation that the pressure measured in the distal stump of an occluded canine coronary (or femoral or carotid) artery ro...

The Advent of Sperm Proteomics has Arrived

Sperm proteomics is the identification and functional study of sperm proteins. It is based on the separation of proteins to generate a sample suitable for mass spectrometry and subsequent protein identification. Various proteomic approaches can be employed to study sperm proteins. Currently it has led to the identification and cataloging of thousands of sperm proteins. Ultimately, the goal is t...